Publications(short)
A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn’s diseaseLowe, S.C., Leitman, M., Yan, N., Hoffmann, A. Front. Immunol 2025 Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic agingChia, J.J., Singh, A., Lin, Y.S., Popko, N., Mastro, D., Liu, Y., Tran, T., King, J.K., Rao, D.S., Hoffmann, A. Cell Rep 2025 Population dynamics modeling reveals that myeloid bias involves both HSC differentiation and progenitor proliferation biasesSingh, A., Chia, J.J., Rao, D.S., Hoffmann, A. Blood 2025 Gene regulatory logic of the interferon-β enhancer is characterized by two selectively deployed modes of transcription factor synergySchiffman, A., Cheng, Z., Ourthiague D., Hoffmann, A. PNAS 2025 Modeling heterogeneous signaling dynamics of macrophages reveals principles of information transmission in stimulus responsesGuo, X., Adelaja, A., Singh, A., Wollman, R., Hoffmann, A. Nat Comm 2025