NF-κB RelB suppresses the inflammatory gene expression programs of dendritic cells by competing with RelA for binding to target gene promotersNavarro, H.I., Daly, A.E., Rodriguez, B., Wu, S., Ngo, K.A., Fraser, A., Schiffman, A., Liu, Y., Smale, S.T., Chia, J.J., Hoffmann, A. Cell Discovery 2025
IRF1 cooperates with ISGF3 or GAF to form innate immune de novo enhancers in macrophagesChavaz, C., Lin, K., Malveaux, A., Gorin, A., Brizuela, S., Cheng, Q.J., Hoffmann, A. Sci Signal. 2025
Single-cell stimulus-response gene expression trajectories reveal the stimulus specificities of dynamic responses by single macrophagesSheu, K.M. Pimplaskar, A. Hoffmann, A. Mol Cell. 2024
Direct observation correlates NFκB cRel in B cells with activatingand terminating their proliferative programVaidehi Narayanan, H., Xiang, M.Y., Chen, Y., Huang, H., Roy, S., Makkar, H., Hoffmann, A., Roy, K. PNAS 2024
Dynamical and combinatorial coding by MAPK p38 and NFκB in the inflammatory response of macrophages. Luecke, S., Guo, X., Sheu, K., Singh, A., Lowe, S.C., Han, M., Diaz, J., Lopes, F., Wollman, R., Hoffmann, A Mol Syst Biol. 2024