Single-cell stimulus-response gene expression trajectories reveal the stimulus specificities of dynamic responses by single macrophagesSheu, K.M. Pimplaskar, A. Hoffmann, A. Mol Cell. 2024
Direct observation correlates NFκB cRel in B cells with activatingand terminating their proliferative programVaidehi Narayanan, H., Xiang, M.Y., Chen, Y., Huang, H., Roy, S., Makkar, H., Hoffmann, A., Roy, K. PNAS 2024
Dynamical and combinatorial coding by MAPK p38 and NFκB in the inflammatory response of macrophages. Luecke, S., Guo, X., Sheu, K., Singh, A., Lowe, S.C., Han, M., Diaz, J., Lopes, F., Wollman, R., Hoffmann, A Mol Syst Biol. 2024
Stimulus-response signaling dynamics characterize macrophage polarization states.Singh, A., Sen, S., Iter, M., Adelaja, A., Luecke, S., Guo, X., Hoffmann, A. Cell Systems. 2024.
Co-imaging of RelA and c-Rel reveals features of NFkB signaling for ligand discriminationShah Md Toufiqur Rahman, Apeksha Singh, Sarina Lowe, Mohammad Aqdas, Kevin Jiang, Haripriya Vaidehi Narayanan, Alexander Hoffmann, and Myong-Hee Sung Cell Rep. 2024