Publications(short)
Quantifying information accumulation encoded in the dynamics of biochemical signalingTang, Y., Adelaja, A., Ye, F., Deeds, E., Wollman, R., Hoffmann, A. Nature Commun 2021 NF-κB responds to absolute differences in cytokine concentrations Son, M., Wang A.G., Tu, H., Metzig, M.O., Patel, P., Husain, K., Lin, J., Murugan, A., Hoffmann, A., Tay, S. Science Signaling 2021 An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisionsMetzig, M.O., Tang, Y., Mitchell, S., Taylor, B., Foreman, R., Wollman, R., Hoffmann, A. Mol Syst Biol. 2020 IκBα Nuclear Export Enables 4-1BB-Induced cRel Activation and IL-2 Production to Promote CD8 T Cell ImmunityLisiero, D.N., Cheng, Z., Tejera, M.M., Neldner, B.T., Warrick, J.W., Wuerzberger-Davis, S.M., Hoffmann, A., Suresh, M., Miyamoto, S. J Immunol 2020 Dissecting the Regulatory Strategies of NFκB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation LogicsNgo, K.A., Kishimoto, K., Davis-Turak, J., Pimplaskar, A., Cheng, Z., Spreafico, R., Chen, E.Y., Tam, A., Ghosh, G., Mitchell, S., Hoffmann, A. Cell Rep 2020